Every year, an estimated 7.9 million infants (6% of worldwide births) are born with serious birth defects. Although some congenital defects can be controlled and treated, an estimated 3.2 million of these children are disabled for life. Moreover, birth defects are the leading cause of infant mortality in the United States. But where do these defects come from? Although some birth defects are inherited, others are a product of harmful environmental factors known as teratogens, and still others are multifactorial, resulting from a complex interaction of genetic and environmental influences.
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